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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Autofluorescence of NADH is a new biomarker for sorting and characterizing cancer stem cells in human glioma

Fig. 5

The invasion ability and TMZ resistance of NADHhigh glioma cells are similar to the ability of CD133+ and CD15+ subpopulation in glioma cells. a The quantitative histograms of invasion showed that invasion ability was significantly increased in NADHhigh, CD133+, and CD15+ LN229 and GBM1 cells. b Effect of TMZ resistance in CD133, CD15, and NADH. IC50 of TMZ in CD133+ and NADHhigh was higher than in CD133, and NADHlow of GBM1 and LN229. The similar result was in CD15 of GBM1, but IC50 of TMZ in CD15 of LN229 was not different. All data are presented as the means ± SD. **p < 0.01, ***p < 0.001 (n = 3 independent experiments)

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