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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Exposure to blue light stimulates the proangiogenic capability of exosomes derived from human umbilical cord mesenchymal stem cells

Fig. 6

Blue light increased miRNAs (MiR-135b and MiR-499a)-MEF2C signaling in MSC-Exs. a Transmission electron microscopy analysis of MSC-derived exosomes. b Western blot analysis of the expression of exosomes enriched markers HSP 70 and CD 9 on the exosomes. c, d qRT-PCR for miR-135b-5p and miR-499a-3p derived from MSCs or MSC-Exs as indicated treatments. The P values were calculated by two-sided Student’s t test. **P < 0.01; ****P < 0.0001. e Western blot analysis of MEF2C expression in MSCs as indicated treatments. Compiled data from three independent experiments is shown. Columns, mean; bars, ± SD; *P < 0.05. f qRT-PCR for miR-135b-5p and miR-499a-3p derived from MSCs or MSC-Exs as indicated treatments. The P values were calculated by two-sided Student’s t test. ****P < 0.0001

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