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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Treatment with adipose tissue-derived mesenchymal stem cells exerts anti-diabetic effects, improves long-term complications, and attenuates inflammation in type 2 diabetic rats

Fig. 5

Multiple ADSC infusions attenuated lung disease in long-term T2DM complication rats. a Representative lung section staining with H&E, PAS, and Masson’s trichrome; bars = 20, 10, and 50 μm. b Lung injury scores were graded using H&E-stained sections. c Ratio of PAS staining-positive area to total area. d Ratio of Masson staining-positive area to total area. e, f Immunofluorescence and quantification of α-SMA and collagen I area; bars = 100 μm. g, h Quantitative reverse transcriptase polymerase chain reaction analysis of gene expression in lung tissue from control, T2DM, and MSC groups; results are presented relative to those of control rats, set as 1. N = 6 rats per group; *p < 0.05, **p < 0.01

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