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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: LncRNA Neat1 mediates miR-124-induced activation of Wnt/β-catenin signaling in spinal cord neural progenitor cells

Fig. 7

The motor function evaluation of SCI animals and the regulatory mechanism of miR-124 on SC-NPCs. a BMS scores were determined at the particular point in time (1, 2, and 3 weeks) after miR-124 treatment. Mir-124-treated animals had significantly higher locomotor scale scores than control mice at 1 and 2 weeks. Error bars represent the mean ± SD of (at least) triplicate experiments. **p < 0.01. b Proposed regulatory mechanism of miR-124-NEAT1-Wnt/β-catenin signaling in SC-NPCs. The diagram shows that Neat1 acts as a key mediator between miR-124 and Wnt/β-catenin signaling in regulating SC-NPC behavior

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Stem Cell Research & Therapy

ISSN: 1757-6512