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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: YAP as a key regulator of adipo-osteogenic differentiation in human MSCs

Fig. 4

Effects of gene manipulations on YAP relative to osteogenic differentiation. YAP expression level in MSCs after being forced to be downregulated and upregulated as quantitated by q-PCR (a). Alizarin red staining shows calcium content and quantitative evaluation of Alizarin red staining in control, YAP-KD, and YAP-O/E MSCs (b, c). Oil Red O staining shows lipid contents and quantification value (d, e). Quantitative data are shown as mean ± SEM; n = 3, *P < 0.05, **P < 0.01, Student’s t test. NS, no significant difference

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