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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Aspirin inhibits RANKL-induced osteoclast differentiation in dendritic cells by suppressing NF-κB and NFATc1 activation

Fig. 5

Aspirin treatment improves bone healing in the rat mandibular defect model. a The diagram above shows the establishment process of the alveolar bone defect model in a rat. b Two weeks after the surgery, the rate of bone defect healing in the aspirin group was much faster than that in the control group (P < 0.05). c Two months later, aspirin showed a clear benefit on the defect healing ratio compared to the control group (P < 0.01). The blue boxes in b and c are the mandibular defect area generated at the beginning of surgery. All experiments are representative of three replicates. *P < 0.05, **P < 0.01

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