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Table 1 The expansion folds of UCB-CD34+ cells under different coculture conditions

From: Wharton’s jelly mesenchymal stem cell-based or umbilical vein endothelial cell-based serum-free coculture with cytokines supports the ex vivo expansion/maintenance of cord blood hematopoietic stem/progenitor cells

N = 6

UMC

UEC

UC

UM

UE

TNCs

312.52 ± 100.68*,^

177.57 ± 51.16*,^

74.00 ± 42.94*,^

4.03 ± 3.82

6.42 ± 4.87*

CD34+ cells

90.17 ± 67.00*,^

68.72 ± 56.310*,^

24.50 ± 19.49*,^

1.40 ± 1.65

2.60 ± 2.54

CD34 + CD38- cells

423.07 ± 300.43*,^

435.15 ± 308.16*,^

222.99 ± 179.30*,^

2.92 ± 2.39

19.10 ± 22.88

  1. *Comparing the cell counts before cultivation (day 0) and after harvest (day 10), the folds of expansion of TNCs, CD34+ cells, and CD34 + CD38− cells, p < 0.05
  2. ^Comparing the cell counts with cytokines (UMC, UEC, UC) and without cytokines (UM, UE) at day 10, the folds of expansion of TNCs, CD34+ cells, and CD34+CD38− cells, p < 0.05