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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: PAMAM-cRGD mediating efficient siRNA delivery to spermatogonial stem cells

Fig. 2

Toxicity profile of the G5-cRGD-mediated delivery system. a The viability of the SSC line incubated with G5 and G5-cRGD nanoparticles at various concentrations by CCK-8 assay. b The viability of the SSC line transfected with G5-siRNA and G5-cRGD-siRNA complexes at different N/P ratios for 24 h, as evaluated by CCK-8 assay. The final siRNA concentration of each sample was 100 nM. Lipo2000 was used as a positive control. Statistical significance was determined by applying the Student’s t test. Data are presented as mean ± standard deviation (SD, n = 3). *p < 0.05, **p < 0.01

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