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Table 2 Available clinical trials of the application of MSCs in AKI

From: Current understanding of the administration of mesenchymal stem cells in acute kidney injury to chronic kidney disease transition: a review with a focus on preclinical models

ClinicalTrials.gov identifier

Year

Aim

MSC type

Enrollment

Phase

Status

Outcomes

NCT00733876

2008

For the prevention of developing AKI after cardiac surgery

Allogeneic

16

Phase I

Completed

Safe and effective

NCT01602328

2017

For the treatment of AKI after cardiac surgery

Allogeneic

156

Phase II

Terminated

Safe but not effective

NCT01275612

2018

For the treatment of cisplatin-induced AKI in cancer patients

Allogeneic

NM

Phase I

Withdrawn

NM

NCT03015623

2018

For the treatment of AKI regardless of the underlying reasons

Allogeneic MSCs combined with a biologic device

24

Phase I

Recruiting

Date not published

  1. MSCs mesenchymal stem cells, AKI acute kidney injury, NM not mentioned