Current understanding of the administration of mesenchymal stem cells in acute kidney injury to chronic kidney disease transition: a review with a focus on preclinical models

Table 3 Failed attempts of MSC treatment in animal models

Reference	Year	Sample	Model	Renal outcomes
Rosselli et al. [103]	2015	Cats	Unilateral I/R injury	No changes in renal function, UP/C, SMA, and histopathologic scoring
Fang et al. [104]	2008	Mice	HgCl₂	No contribution to renal tubular cells regeneration
Kankuri et al. [106]	2015	Rats	Bilateral I/R injury	Exacerbation of renal function

MSCs mesenchymal stem cells, I/R ischemia-reperfusion, UP/C urine protein: creatinine, SMA smooth muscle actin

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