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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Small extracellular vesicles derived from embryonic stem cells restore ovarian function of premature ovarian failure through PI3K/AKT signaling pathway

Fig. 1

Characterization of ESCs and ESCs-sEVs. a Immunofluorescence detected the pluripotency markers in ESCs, including Oct-4, SSEA-4, Nanog, and TRA-1-81. Scale bars = 50 μm. b The morphology of ESCs-sEVs by TEM. Scale bars = 200 μm. c ESCs-sEVs were positive for CD9, CD63, and TSG101 and negative for GM130, Actin, and Lamin A/C, as shown by Western-blotting analysis. d Particle size distribution of ESCs-sEVs was determined by Flow Nano Analyzer

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Stem Cell Research & Therapy

ISSN: 1757-6512