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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Melatonin promotes the BMP9-induced osteogenic differentiation of mesenchymal stem cells by activating the AMPK/β-catenin signalling pathway

Fig. 2

Melatonin enhances BMP9-inducedOPN and OCN expression and matrix mineralization in C3H10T1/2. a Alizarin red S staining. b, c Immunohistochemical staining of osteocalcin (OCN) or osteopontin (OPN). d The expression of osteogenesis-related genes RUNX2, Osterix, Col1 and BMP2 mRNA. e Alizarin red S staining of primary MSCs. Compared with the control group, ^^p < 0.01 and ^^^p < 0.001; compared with the BMP9 group, *p < 0.05 and **p < 0.01

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