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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: A comprehensive proteomics profiling identifies NRP1 as a novel identity marker of human bone marrow mesenchymal stromal cell-derived small extracellular vesicles

Fig. 5

Functional pathway analysis of plasma membrane proteins from the twofold enriched dataset of hBM-MSC-sEVs. a Functional annotation of plasma membrane proteins from the twofold enriched dataset of hBM-MSC-sEVs showed an increase (activation z-score of ≥ + 2) in those categories: migration of cells, cell movement of leukocytes, invasion of cells, chemotaxis, vasculogenesis, and leukocyte migration. Shown in bold are the common proteins further inquired for the hierarchical network (b) of plasma membrane proteins from the twofold enriched dataset of hBM-MSC-sEVs highlighting the associated activated functions (activation z-score ≥ + 2), such as migration of cells, cell movement of leukocytes, invasion of cells, chemotaxis, vasculogenesis, and leukocyte migration with the NRP1 activated pathways highlighted

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Stem Cell Research & Therapy

ISSN: 1757-6512