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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Activation of type I interferon antiviral response in human neural stem cells

Fig. 5

Poly(A:U), but not GS9620 and motolimod, is able to induce the IFN-β upregulation in hNSCs. a RT-qPCR analysis was performed to detect the IFN-β expression in NSCs transfected with poly(A:U) (1 μg), GS9620(1 μM), and motolimod (20 μM) for the indicated time points. b RT-qPCR analysis was performed to detect the IFN-β expression in PMA-primed THP-1 cells transfected with poly(A:U) (1 μg) and human PBMCs transfected with GS9620 (1 μM) and motolimod (20 μM). The experiments were performed in triplicate, and the error bars represented the SD. Student’s t test was used for statistical analysis. *p < 0.05, **p < 0.01, ***p < 0.001. n.s., non-significant

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