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Table 5 Quantification of extracellular vesicles in PBMCsec

From: Reproducibility of GMP-compliant production of therapeutic stressed peripheral blood mononuclear cell-derived secretomes, a novel class of biological medicinal products

Sample

Concentration (particles/mL)

Mean particle size (nm)

PBMCsec 1

1.8 × 109 ± 1.58 × 108

215.6 ± 3.4

PBMCsec 2

1.72 × 109 ± 6.75 × 107

214.2 ± 5

PBMCsec 3

1.93 × 109 ± 8.93 × 107

215.3 ± 3.7

Placebo

7.27 × 108 ± 7.78 × 107

225.9 ± 17.9

PBS

5.34 × 107 ± 1.45 × 107

171.2 ± 20

Mean PBMCsec batches

1.82 × 109

215.03

SD PBMCsec batches

8.65 × 107

0.6

% deviation PBMCsec batches

4.76

0.28