Fig. 6

a Representative photomicrographs of Glut-1-positive endothelial cell proliferation in PVWM across groups. Scale bar = 50 μm. b Quantitative analysis of Glut-1 cell counts across brain regions; two-way ANOVA applied. c Quantitative analysis of Glut-1-positive percent area in PVWM across groups. d Representative photomicrographs of Desmin-SMA double label fluorescent staining showing poor (a, FGR) and good (b, FGR+UCBC) co-localization within the neurovascular unit. Scale bar = 100 μm. Asterisk denotes significant difference between FGR vs. AGA groups. Number sign denotes significant difference between FGR+UCBC vs. all other groups. e Quantitative analysis of co-localization coefficients (M1 and M2), showing significant reduction (*) in co-localization coefficients in FGR lambs, which is normalized with UCBC therapy; significant differences accepted at p < 0.05