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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathway-regulated autophagy and upregulating the circulating of CD8+CD28 T cells

Fig. 6

HO-1, JNK/Bcl-2 signal pathway- and autophagy-related protein expression in ovarian tissues by western blot analysis. a The HO-1, JNK/Bcl-2 signal pathway- and autophagy-related protein expression in PVDF membrane. Quantification of b JNK, c p-JNK, d Bcl-2, e HO-1, f LC3II/I, g Beclin1, h p62, and i Atg5 protein expression. *P < 0.05, **P < 0.01, ***P < 0.001 vs DMSO, GC group, or NC group, separately. DMSO, dimethylsulfoxide; HO-1, heme oxygenase-1; NC, empty vector; POF, premature ovarian failure; UCMSCs, umbilical cord mesenchymal stem cells

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