Fig. 2From: hUCMSC-extracellular vesicles downregulated hepatic stellate cell activation and reduced liver injury in S. japonicum-infected micehUCMSC-EVs prolong the survival of S. japonicum-infected mice. a Time schedule for parasite infection and injections of PBS, hUCMSCs, or hUCMSC-EVs. Mice were infected percutaneously with 26 S. japonicum cercariae at day 0 and treated with hUCMSCs/hUCMSC-EVs by tail vein injection at day 28/35/42/49 post-infection. The animals were subjected to an 80-day survival study. MSCs, hUCMSCs; EVs, hUCMSC-EVs. b The survival curves of mice in each group. *P < 0.05, compared with the PBS groupBack to article page