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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Mesenchymal stem cells promote human melanocytes proliferation and resistance to apoptosis through PTEN pathway in vitiligo

Fig. 5

MSCs protect human melanocytes from dying by regulation of PTEN pathway. a High PTEN expression and oxidative stress damage melanocytes, leading to melanocyte death and eventually initiating vitiligo. b High PTEN expression and oxidative stress destroy melanocytes, while the presence of MSCs, which regulate PTEN expression and oxidative stress, rescues melanocytes from dying and restores their function of pigment production

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