Fig. 6
CAC administration modulates the recruitment of neutrophils to the ischemic tissues. a Functional analysis of the proteomic changes detected in response to CACs (SE vs SC, p < 0.05), indicated that these changes were involved in neutrophil recruitment (migration, adhesion, and transmigration) and neutrophil participation of the immune response. Pathways were obtained with the IPA software. b Detection of mouse neutrophils by IHC in the left hind limb frontal muscle labeling with Ly-6G antibody on days 2 and 4 in treated, non-treated, and sham mice. c Determination of neutrophils number (neutrophils/mm2) in treated, non-treated, and sham mice. Data were presented as mean ± SEM. Significant differences were found between SH (with no neutrophils) and the other groups: *p value < 0.05, ***p value < 0.001, by one-way ANOVA and Tukey post hoc test