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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: The therapeutic impact of human neonatal BMSC in a right ventricular pressure overload model in mice

Fig. 7

The expression of matrix metalloproteinase (MMP) 9 in vitro (a). Compared to infant and children group, higher migration and MMP 9 expression in neonate BMSC. Quantitative real-time PCR analysis for MMP 9, VEGF, VEGFR-1, VEGFR-2, and PKG-1 in mouse heart samples. Four weeks post-operation and treatment, heart samples were collected for PCR analysis. The results show that MMP 9 (b), VEGF, VEGFR-1, VEGFR-2, and PKG-1 (c) were significantly increased in mice that received stem cell therapy after PAB, compared to those in the sham operation and PAB with the placebo treatment groups. *P < 0.05

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