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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Transforming growth factor β1 accelerates and enhances in vitro red blood cell formation from hematopoietic stem cells by stimulating mitophagy

Fig. 4

TGF-β1 regulates mitophagy gene expression during terminal erythroid differentiation. Cultured cells from day 12 of control and TGF-β1 set were subjected to quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) analysis to quantify the mitophagy-inducing mRNAs. Cells cultured with TGF-β1 show a significant increase in the level of aBNIP3L, bUlk1, cBeclin1, dLC3a, eLC3b, fGABARAPL1, and gGABARAPL2. Results are presented as mean ± SEM from independent experiments done with five different donor samples. *p < 0.05; **p < 0.01

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Stem Cell Research & Therapy

ISSN: 1757-6512