Fig. 3From: Mesenchymal stem cells regulate the Th17/Treg cell balance partly through hepatocyte growth factor in vitroThe regulatory effect of HGF secreted by MSCs on cytokine mRNA expression in CD4+ T cells analysed by qPCR. The results showed that MSCs significantly increased IL-10 (p < 0.05, a) and TGF-β (p < 0.01, b) mRNA expression and inhibited IL-17 (p < 0.01, c) and IL-6 (p < 0.05, d) mRNA expression in CD4+ T cells. However, the MSC-induced effects were inhibited by an anti-HGF antibody (p < 0.05 or p < 0.01) (n = 3; *p < 0.05 or **p < 0.01 vs. the CD4+ group; #p < 0.05 or ##p < 0.01 vs. the MSC+CD4+ group). MSCs, mesenchymal stem cells; rmHGF, recombinant mouse hepatocyte growth factor; qPCR, quantitative polymerase chain reactionBack to article page