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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Tumor necrosis factor α in aGVHD patients contributed to the impairment of recipient bone marrow MSC stemness and deficiency of their hematopoiesis-promotion capacity

Fig. 6

TNF-α in aGVHD BM supernatants suppressed the hematopoietic supporting capacity of MSCs. a The CFC morphologic characteristics in the bulk culture of long-term culture-initiating cells were observed under a reverted light microscope. Bars in a represent 200 μm. b The CFCs numbers in the presence of anti-TNF-α neutralization antibody partially recovered. **p < 0.01, compared with aGVHD groups, n = 5

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