Fig. 8From: Tumor necrosis factor α in aGVHD patients contributed to the impairment of recipient bone marrow MSC stemness and deficiency of their hematopoiesis-promotion capacityTNF-α has a pivotal role in aGVHD mediated MSC injury. a aGVHD induced-cytokine storm injure the self-renewal, multipotency, and hematopoietic promotion of bone marrow mesenchymal stem cells (BM MSC). b Blockage of tumor necrosis factor α (TNF-α) partially rescue the MSC propertiesBack to article page