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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Microvesicles derived from human Wharton’s jelly mesenchymal stem cells enhance autophagy and ameliorate acute lung injury via delivery of miR-100

Fig. 2

MSC-MVs attenuate the BLM-induced apoptosis and inflammation via transferring miR-100. a, b Annexin V-FITC/PI apoptotic assay (a) and levels of IL-6, IL-8, and TNF-α in cell supernatant (b) in L2 cells in the groups of control, BLM, BLM+mimic NC, and BLM+miR-100 mimic. c, d Annexin V-FITC/PI apoptotic assay (c) and levels of IL-6, IL-8, and TNF-α in cell supernatant (d) in L2 cells in the groups of control, BLM, BLM+MVs, BLM+NCI-MVs, and BLM+miR-100I-MVs. Data are presented as the means ± SD (n = 3). **p < 0.01, vs. control; ##p < 0.01, vs. BLM+mimic NC; $$p < 0.01, vs. BLM; &&p < 0.01, vs. BLM+NCI-MVs

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Stem Cell Research & Therapy

ISSN: 1757-6512