Skip to main content
Fig. 9 | Stem Cell Research & Therapy

Fig. 9

From: Genome-wide identification of long noncoding RNAs and their competing endogenous RNA networks involved in the odontogenic differentiation of human dental pulp stem cells

Fig. 9

The location and function of G043225. a–c Expression of G043225 (green) as detected by fluorescence in situ hybridization array. Nuclei (blue) were counterstained with DAPI. d–g G043225 knockdown inhibited mineralization, indicated by Alizarin Red staining at 14 days after odontogenic induction. h–k G043225 knockdown inhibited mineralization, indicated by ALP staining at 7 days after odontogenic induction. l, m The expression level of DSPP and RUNX2 decreased in the shRNA-G043225 group at 14 days after odontogenic differentiation using qRT-PCR. n–p Western blot analysis shows the expression level of DPSS and RUNX2 decreased in the shRNA-G043225 group after odontogenic differentiation for 14 days. GAPDH was used as an internal control. Data represent means ± SD. *P < 0.05, **P < 0.01 compared with differentiated shRNA-ctrl group

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512