Fig. 1From: DNA methylation of noncoding RNAs: new insights into osteogenesis and common bone diseasesHypermethylation at the CpG sites of miR-149 promoter inhibited the expression of miR-149, thereby eliminating the inhibitory effect on SDF-1 and activating the SDF-1/CXCR4 signaling, which ultimately induced osteogenic differentiation of MSCs [35]Back to article page