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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: A model study for the manufacture and validation of clinical-grade deciduous dental pulp stem cells for chronic liver fibrosis treatment

Fig. 6

Hepatogenic capacity of P10 hDPSC products for the WCB. a The hepatogenic capacity of the P10 hDPSCs was tested by hepatocyte-specific gene expression 4 weeks after hepatogenic inductive culture by qRT-PCR assay. The results are shown as the ratios of the expression of 18S and are shown as the average ratio. AFP, alpha fetoprotein gene; ALB, albumin gene; ARG2, arginase 2 gene; ASL, argininosuccinate lyase gene; ASS1, argininosuccinate synthase 1 gene; ATP7B, ATPase copper transporting beta gene; CPS1, carbamoyl-phosphate synthase 1 gene; CYP3A7, cytochrome P450 family 3 subfamily A member 7 gene; FAH, fumarylacetoacetate hydrolase gene; KRT18, keratin 18 gene; NAGS, N-acetylglutamate synthase gene; TF, transferrin gene; TTR, transthyretin. N/A, not applicable. The graph bars show the mean. b The P10 hDPSCs were stimulated with and without H2O2 to analyze the expression of stanniocalcin 1 (STC1) by qRT-PCR. The results are calculated as the ratios of the expression of 18S and are shown as the average ratio. a, bn = 3 for all groups. N/A, not applicable

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