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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: LAMA2 regulates the fate commitment of mesenchymal stem cells via hedgehog signaling

Fig. 5

LAMA2 regulated osteogenic differentiation of MSCs via hedgehog signaling pathway. aLAMA2 knockdown enhanced the expression of SHH, GLI1, GLI2, and RUNX2. b Double knockdown of LAMA2 and GLI2 validated by Western blot analysis. c ALP and ARS staining in the control, LAMA2 knockdown, and LAMA2/GLI2 knockdown groups. d Oil Red O staining in the control, LAMA2 knockdown, and LAMA2/GLI2 knockdown groups. **p < 0.01, ***p < 0.001

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