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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Mesenchymal stem cells ameliorate myocardial fibrosis in diabetic cardiomyopathy via the secretion of prostaglandin E2

Fig. 3

MSC infusion ameliorated myocardial fibrosis in DCM rats. At the end of the experiment, Sirius Red staining (a–c) for the hearts of three groups was performed, and quantification of the collagen deposition (d) was also calculated to reflect the degree of myocardial fibrosis. Moreover, the mRNA levels of TGF-β in the hearts were detected by PCR (e), and the protein levels of Collagen I (f) and Collagen III (g) in the hearts were determined by ELISA assay. n = 3, Scale bar = 1000 μm (upper), 50 μm (lower), *P < 0.05, **P < 0.005, ***P < 0.0005. Inset and arrow show partially enlarged area

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