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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Targeting prostate cancer stem-like cells by an immunotherapeutic platform based on immunogenic peptide-sensitized dendritic cells-cytokine-induced killer cells

Fig. 3

FACS analysis of DC-activated CIK cells. a FACS analysis of CD3+CD56+ CIK subset cells upon co-culture of CIK cells with peptide-sensitized DC cells (on day 0 and day 14) in two representative preparations from PBLs. Results showed that the population of CD3+CD56+ CIK cells showed a significant increase after a 14-day DC-CIK co-culture. b FACS analysis showed that the CIK cells on day 14 co-culture contained less CD3+CD4+ T cells (CD4 T cells) and CD3CD56+ NK cells but more CD3+CD4 T cells (CD8 T cells) as compared to CIK cells on day 0 culture. c FACS analysis of CIK cell population from a total of 21 samples of PBLs. Summary results showed that the modified CIK culture protocol with stimulation by peptide-loaded DC cells could generate more population of CIK cells and decreased ratio of CD4+/CD8+ T cells. **P < 0.01; ***P < 0.001 versus cells collected on day 0

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