Fig. 7
From: IGF-1C domain–modified hydrogel enhanced the efficacy of stem cells in the treatment of AMI
CS-IGF-1C hydrogel co-transplanted with hP-MSCs decreased collagen deposition and inflammatory cells. a Representative Masson’s trichrome staining of heart sections at day 30. Scale bar represents 1 mm. b Quantitative analysis of the area of fibrosis. *P < 0.05 versus PBS; **P < 0.01 versus PBS. c HE staining of heart sections in peri-infarction area on day 14. Scale bar, 100 μm. d Quantification of inflammatory cells. *P < 0.05 versus PBS. e Expression levels of caspase 9 and TNF-α by RT-PCR in each group on days 30 and 14, respectively. Data are expressed as mean ± SEM. *P < 0.05 versus PBS