Fig. 8
From: IGF-1C domain–modified hydrogel enhanced the efficacy of stem cells in the treatment of AMI
Schematic illustration of CS-IGF-1C hydrogel with hP-MSCs for treatments of acute myocardial infarction. In this study, BLI was applied for tracking the survival of hP-MSCs by Fluc imaging. CS-IGF-1C hydrogel provides a conducive microenvironment for cells and significantly improves the survival of hP-MSCs in mouse MI model, which could prolong the therapeutic effect of hP-MSCs by promoting angiogenesis, anti-apoptosis, and inhibiting fibrosis, and further promote function recovery of the damaged myocardium