Fig. 1

Transcriptome analysis of the human MSCs exposed to different concentrations of human platelet lysate. a Cell number counting after human MSCs exposed to 1%, 2%, and 5% PL in DMEM. Cells were plated onto p12 plates at 2 × 10⁴ cells per well and the cell number was counted 5 days later. b PCA of human MSCs exposed to different concentrations of human platelet lysate. c KEGG pathway enrichment of cluster 2 derived from the gene expression pattern clustering analysis. d Protein-protein interaction analysis of the genes derived from the MAPK signaling pathway of cluster 2. NC, negative control, Dulbecco’s modified Eagle’s medium-high glucose; PL, human platelet lysate; An asterisk indicates P < 0.05