Fig. 2
From: Paracrine effects of intraocularly implanted cells on degenerating retinas in mice
Transplantation of SDSCs in RhoP23H/+ recipients. a Comparison of retinal thickness between mutant (homozygous RhoP23H/P23H and heterozygous RhoP23H/+) and wild-type mice (Rho+/+) in stack bar graphs. b Representative P40 retinal cross paraffin sections of the three genotypes stained with the rod markers rhodopsin (Rho for the outer segment) and recoverin (Rec for the inner segment) and the cone marker opsin. c The optokinetic response (OKR) of the three different genotypes of mice at postnatal days 30 to 90. d Number of nuclei per column in the outer nuclear layer. e Vision assessment by an OKR system for RhoP23H/+ mice either subretinally injected with 2 μl of 2 × 105 SDSCs or PBS as a control. GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; IS, inner segment; OS, outer segment; c/d, cycles/degree