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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Ultrasound-targeted microbubble destruction optimized HGF-overexpressing bone marrow stem cells to repair fibrotic liver in rats

Fig. 6

Immunohistochemical staining analysis using collagen I and vimentin and the relative quantitative curve using ImagePro plus software. (A1) Immunohistochemcial staining for collagen I in the four groups at each detection time(× 200), (B1) immunohistochemcial staining for vimentin in the four groups (× 200), (C) immunohistochemcial staining for α-SMA(× 200), and (A2, B2, C2) the relative quantification of immunohistochemistry collagen I, α-SMA, and vimentin. As was shown in the figure, the amount of collagen I, α-SMA, and vimentin were significantly decreased by the BMSCs treatment after 4 weeks in BMSCs-HGF/UTMD group. Also, the presence of fibers gradually decreased to a relatively low level after 8 weeks. (*p < 0.05, compared with the other three groups at the same time; *# < 0.05, made self-contrast at different points)

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