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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Autophagy modulation altered differentiation capacity of CD146+ cells toward endothelial cells, pericytes, and cardiomyocytes

Fig. 4

ELISA assay (a, b). Measuring protein levels of VEGFR-1, VEGFR-2, and Tie-1, Tie-2, and Ang-1 after autophagy modulation (a; n = 3). It seems that autophagy stimulation could increase differentiation potential, but these changes did not reach statistically significant levels. The effect of autophagy stimulation/inhibition on the inflammatory status of differentiating CD146+ cells (b; n = 3). It seems that autophagy stimulation could decrease significantly the production of TNF-α and IL-6 after treatment with 50-μM Met. Student t test. ***p < 0.001

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