Fig. 4
From: GVHD-derived plasma as a priming strategy of mesenchymal stem cells
Immunosuppressive potential of MSCs. a Representative CFSE histogram of activated T cell (black histogram) and activated T cell co-cultured with MSCs (T cell—MSCs, gray histogram). b T cell proliferation after co-culture with control MSCs (primed with pooled plasma from healthy donors) and MSCs primed with acute GVHD (GA 1-7) and chronic GVHD (GC 1-12) individual plasma samples. c Percentage of aGVHD and cGVHD plasmas which succeeded or failed to increase the immunosuppressive potential of primed MSCs. d T cell proliferation after co-culture with 5%, 15%, and 25% of the pool of aGVHD and cGVHD plasmas that enhanced the MSC immunosuppressive function. Results are presented as mean concentration ± SD of three independent experiments. *p < 0.05, **p < 0.01, and ****p < 0.0001