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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: GVHD-derived plasma as a priming strategy of mesenchymal stem cells

Fig. 6

Generation of Tregs and expression of adhesion molecules on MSC surface. a The percentage of CD4+CD25+FOXP3+ in PBMCs cultured with control MSCs and MSCs primed with aGVHD plasmas (GA1, GA3, GA6, GA7) and cGVHD (GC3, GC4, GC5, GC6, GC7) was assessed by flow cytometry. This technique also was used to determine the expression of VCAM-1 (b) and ICAM-1 (c) on control and primed MSCs. d ICAM-1 expression was determined also in MSCs primed with crescent concentrations of a pool of cGVHD plasmas. Results are presented as mean concentration ± SD of three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001

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