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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Single-cell RNA-seq highlights heterogeneity in human primary Wharton’s jelly mesenchymal stem/stromal cells cultured in vitro

Fig. 3

Candidate subpopulations with different functional characteristics. a UMAP visualizing the results of cell clustering. b Bean plots showing expression of several representative DEGs among the six subpopulations. c Pathways significantly enriched for the genes differentially expressed in one subpopulation compared to others. d GO-slim biological process enriched for the genes differentially expressed in one subpopulation compared to others. For c and d, only the top 10 terms with lowest FDR (FDR ≤ 0.05) were present. e Boxplots showing expression of classic MSC marker genes in subpopulations. f Example of candidate markers showing different expression pattern among the five subpopulations (C0–C4). C0, red; C1, olive; C2, yellow; C3, green; C4, blue; C5, purple. IMCC, inflammation mediated by chemokine and cytokine; DNPD, de novo pyrimidine deoxyribonucleotide

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