TY - JOUR AU - Takahashi, K. AU - Yamanaka, S. PY - 2006 DA - 2006// TI - Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors JO - Cell. VL - 126 UR - https://doi.org/10.1016/j.cell.2006.07.024 DO - 10.1016/j.cell.2006.07.024 ID - Takahashi2006 ER - TY - JOUR AU - Takahashi, K. PY - 2007 DA - 2007// TI - Induction of pluripotent stem cells from adult human fibroblasts by defined factors JO - Cell. VL - 131 UR - https://doi.org/10.1016/j.cell.2007.11.019 DO - 10.1016/j.cell.2007.11.019 ID - Takahashi2007 ER - TY - JOUR AU - Takahashi, K. PY - 2014 DA - 2014// TI - Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm JO - Nat Commun VL - 5 UR - https://doi.org/10.1038/ncomms4678 DO - 10.1038/ncomms4678 ID - Takahashi2014 ER - TY - JOUR AU - Nishimura, T. PY - 2017 DA - 2017// TI - Generation of canine induced Extraembryonic endoderm-like cell line that forms both extraembryonic and embryonic endoderm derivatives JO - Stem Cells Dev VL - 26 UR - https://doi.org/10.1089/scd.2017.0026 DO - 10.1089/scd.2017.0026 ID - Nishimura2017 ER - TY - JOUR AU - Parenti, A. PY - 2016 DA - 2016// TI - OSKM induce extraembryonic endoderm stem cells in parallel to induced pluripotent stem cells JO - Stem Cell Rep VL - 6 UR - https://doi.org/10.1016/j.stemcr.2016.02.003 DO - 10.1016/j.stemcr.2016.02.003 ID - Parenti2016 ER - TY - JOUR AU - Hou, P. PY - 2013 DA - 2013// TI - Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds JO - Science. VL - 341 UR - https://doi.org/10.1126/science.1239278 DO - 10.1126/science.1239278 ID - Hou2013 ER - TY - JOUR AU - Ye, J. PY - 2016 DA - 2016// TI - Pluripotent stem cells induced from mouse neural stem cells and small intestinal epithelial cells by small molecule compounds JO - Cell Res VL - 26 UR - https://doi.org/10.1038/cr.2015.142 DO - 10.1038/cr.2015.142 ID - Ye2016 ER - TY - JOUR AU - Long, Y. PY - 2015 DA - 2015// TI - Bromodeoxyuridine promotes full-chemical induction of mouse pluripotent stem cells JO - Cell Res VL - 25 UR - https://doi.org/10.1038/cr.2015.96 DO - 10.1038/cr.2015.96 ID - Long2015 ER - TY - JOUR AU - Li, L. PY - 2019 DA - 2019// TI - The modification of mitochondrial energy metabolism and histone of goat somatic cells under small molecules compounds induction JO - Reprod Domest Anim VL - 54 UR - https://doi.org/10.1111/rda.13304 DO - 10.1111/rda.13304 ID - Li2019 ER - TY - JOUR AU - Zhao, Y. PY - 2015 DA - 2015// TI - A XEN-like state bridges somatic cells to pluripotency during chemical reprogramming JO - Cell. VL - 163 UR - https://doi.org/10.1016/j.cell.2015.11.017 DO - 10.1016/j.cell.2015.11.017 ID - Zhao2015 ER - TY - JOUR AU - Li, X. PY - 2017 DA - 2017// TI - Direct reprogramming of fibroblasts via a chemically induced XEN-like state JO - Cell Stem Cell VL - 21 UR - https://doi.org/10.1016/j.stem.2017.05.019 DO - 10.1016/j.stem.2017.05.019 ID - Li2017 ER - TY - JOUR AU - Moerkamp, A. T. PY - 2013 DA - 2013// TI - Extraembryonic endoderm cells as a model of endoderm development JO - Develop Growth Differ VL - 55 UR - https://doi.org/10.1111/dgd.12036 DO - 10.1111/dgd.12036 ID - Moerkamp2013 ER - TY - JOUR AU - Gu, W. PY - 2016 DA - 2016// TI - Glycolytic metabolism plays a functional role in regulating human pluripotent stem cell state JO - Cell Stem Cell VL - 19 UR - https://doi.org/10.1016/j.stem.2016.08.008 DO - 10.1016/j.stem.2016.08.008 ID - Gu2016 ER - TY - JOUR AU - Panopoulos, A. D. PY - 2012 DA - 2012// TI - The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming JO - Cell Res VL - 22 UR - https://doi.org/10.1038/cr.2011.177 DO - 10.1038/cr.2011.177 ID - Panopoulos2012 ER - TY - JOUR AU - Mathieu, J. PY - 2014 DA - 2014// TI - Hypoxia-inducible factors have distinct and stage-specific roles during reprogramming of human cells to pluripotency JO - Cell Stem Cell VL - 14 UR - https://doi.org/10.1016/j.stem.2014.02.012 DO - 10.1016/j.stem.2014.02.012 ID - Mathieu2014 ER - TY - JOUR AU - Kida, Y. S. PY - 2015 DA - 2015// TI - ERRs mediate a metabolic switch required for somatic cell reprogramming to pluripotency JO - Cell Stem Cell VL - 16 UR - https://doi.org/10.1016/j.stem.2015.03.001 DO - 10.1016/j.stem.2015.03.001 ID - Kida2015 ER - TY - JOUR AU - Lin, Z. PY - 2018 DA - 2018// TI - Fatty acid oxidation promotes reprogramming by enhancing oxidative phosphorylation and inhibiting protein kinase C JO - Stem Cell Res Ther VL - 9 UR - https://doi.org/10.1186/s13287-018-0792-6 DO - 10.1186/s13287-018-0792-6 ID - Lin2018 ER - TY - JOUR AU - Houghton, F. D. PY - 1996 DA - 1996// TI - Oxygen consumption and energy metabolism of the early mouse embryo JO - Mol Reprod Dev VL - 44 UR - https://doi.org/3.0.CO;2-I DO - 3.0.CO;2-I ID - Houghton1996 ER - TY - JOUR AU - Gatie, M. I. AU - Kelly, G. M. PY - 2018 DA - 2018// TI - Metabolic profile and differentiation potential of extraembryonic endoderm-like cells JO - Cell Death Discov VL - 4 UR - https://doi.org/10.1038/s41420-018-0102-1 DO - 10.1038/s41420-018-0102-1 ID - Gatie2018 ER - TY - JOUR AU - Li, P. PY - 2017 DA - 2017// TI - Efficient feeder cells preparation system for large-scale preparation and application of induced pluripotent stem cells JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/s41598-017-10428-5 DO - 10.1038/s41598-017-10428-5 ID - Li2017 ER - TY - JOUR AU - Jin, X. PY - 2019 DA - 2019// TI - ERalpha is required for suppressing OCT4-induced proliferation of breast cancer cells via DNMT1/ISL1/ERK axis JO - Cell Prolif VL - 52 UR - https://doi.org/10.1111/cpr.12612 DO - 10.1111/cpr.12612 ID - Jin2019 ER - TY - JOUR AU - Sun, M. PY - 2018 DA - 2018// TI - Extracellular matrix stiffness controls osteogenic differentiation of mesenchymal stem cells mediated by integrin alpha5 JO - Stem Cell Res Ther VL - 9 UR - https://doi.org/10.1186/s13287-018-0798-0 DO - 10.1186/s13287-018-0798-0 ID - Sun2018 ER - TY - JOUR AU - Shimosato, D. AU - Shiki, M. AU - Niwa, H. PY - 2007 DA - 2007// TI - Extra-embryonic endoderm cells derived from ES cells induced by GATA factors acquire the character of XEN cells JO - BMC Dev Biol VL - 7 UR - https://doi.org/10.1186/1471-213X-7-80 DO - 10.1186/1471-213X-7-80 ID - Shimosato2007 ER - TY - JOUR AU - Kunath, T. PY - 2005 DA - 2005// TI - Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts JO - Development. VL - 132 UR - https://doi.org/10.1242/dev.01715 DO - 10.1242/dev.01715 ID - Kunath2005 ER - TY - JOUR AU - Zhong, Y. PY - 2018 DA - 2018// TI - Isolation of primitive mouse extraembryonic endoderm (pXEN) stem cell lines JO - Stem Cell Res VL - 30 UR - https://doi.org/10.1016/j.scr.2018.05.008 DO - 10.1016/j.scr.2018.05.008 ID - Zhong2018 ER - TY - JOUR AU - Artus, J. PY - 2012 DA - 2012// TI - BMP4 signaling directs primitive endoderm-derived XEN cells to an extraembryonic visceral endoderm identity JO - Dev Biol VL - 361 UR - https://doi.org/10.1016/j.ydbio.2011.10.015 DO - 10.1016/j.ydbio.2011.10.015 ID - Artus2012 ER - TY - JOUR AU - Debeb, B. G. PY - 2009 DA - 2009// TI - Isolation of Oct4-expressing extraembryonic endoderm precursor cell lines JO - PLoS One VL - 4 UR - https://doi.org/10.1371/journal.pone.0007216 DO - 10.1371/journal.pone.0007216 ID - Debeb2009 ER - TY - JOUR AU - Shen, Q. Y. PY - 2019 DA - 2019// TI - Characterization of porcine extraembryonic endoderm cells JO - Cell Prolif VL - 52 UR - https://doi.org/10.1111/cpr.12591 DO - 10.1111/cpr.12591 ID - Shen2019 ER - TY - JOUR AU - Shi, X. PY - 2016 DA - 2016// TI - Differentiation of hepatocytes from induced pluripotent stem cells derived from human hair follicle mesenchymal stem cells JO - Cell Tissue Res VL - 366 UR - https://doi.org/10.1007/s00441-016-2399-5 DO - 10.1007/s00441-016-2399-5 ID - Shi2016 ER - TY - JOUR AU - Frum, T. PY - 2013 DA - 2013// TI - Oct4 cell-autonomously promotes primitive endoderm development in the mouse blastocyst JO - Dev Cell VL - 25 UR - https://doi.org/10.1016/j.devcel.2013.05.004 DO - 10.1016/j.devcel.2013.05.004 ID - Frum2013 ER - TY - JOUR AU - Wicklow, E. PY - 2014 DA - 2014// TI - HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst JO - PLoS Genet VL - 10 UR - https://doi.org/10.1371/journal.pgen.1004618 DO - 10.1371/journal.pgen.1004618 ID - Wicklow2014 ER - TY - JOUR AU - Morgani, S. M. AU - Brickman, J. M. PY - 2015 DA - 2015// TI - LIF supports primitive endoderm expansion during pre-implantation development JO - Development. VL - 142 UR - https://doi.org/10.1242/dev.125021 DO - 10.1242/dev.125021 ID - Morgani2015 ER - TY - JOUR AU - Neri, F. PY - 2012 DA - 2012// TI - Myc regulates the transcription of the PRC2 gene to control the expression of developmental genes in embryonic stem cells JO - Mol Cell Biol VL - 32 UR - https://doi.org/10.1128/MCB.06148-11 DO - 10.1128/MCB.06148-11 ID - Neri2012 ER - TY - JOUR AU - Zheng, J. PY - 2016 DA - 2016// TI - A combination of small molecules directly reprograms mouse fibroblasts into neural stem cells JO - Biochem Biophys Res Commun VL - 476 UR - https://doi.org/10.1016/j.bbrc.2016.05.080 DO - 10.1016/j.bbrc.2016.05.080 ID - Zheng2016 ER - TY - JOUR AU - Lai, P. L. PY - 2017 DA - 2017// TI - Efficient generation of chemically induced mesenchymal stem cells from human dermal fibroblasts JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/srep44534 DO - 10.1038/srep44534 ID - Lai2017 ER - TY - JOUR AU - Cao, S. PY - 2017 DA - 2017// TI - Chemical reprogramming of mouse embryonic and adult fibroblast into endoderm lineage JO - J Biol Chem VL - 292 UR - https://doi.org/10.1074/jbc.M117.812537 DO - 10.1074/jbc.M117.812537 ID - Cao2017 ER - TY - JOUR AU - Zhao, T. PY - 2018 DA - 2018// TI - Single-cell RNA-seq reveals dynamic early embryonic-like programs during chemical reprogramming JO - Cell Stem Cell VL - 23 UR - https://doi.org/10.1016/j.stem.2018.05.025 DO - 10.1016/j.stem.2018.05.025 ID - Zhao2018 ER - TY - JOUR AU - Li, Y. PY - 2011 DA - 2011// TI - Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules JO - Cell Res VL - 21 UR - https://doi.org/10.1038/cr.2010.142 DO - 10.1038/cr.2010.142 ID - Li2011 ER - TY - JOUR AU - Huangfu, D. PY - 2008 DA - 2008// TI - Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds JO - Nat Biotechnol VL - 26 UR - https://doi.org/10.1038/nbt1418 DO - 10.1038/nbt1418 ID - Huangfu2008 ER - TY - JOUR AU - Maherali, N. AU - Hochedlinger, K. PY - 2009 DA - 2009// TI - Tgfbeta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMyc JO - Curr Biol VL - 19 UR - https://doi.org/10.1016/j.cub.2009.08.025 DO - 10.1016/j.cub.2009.08.025 ID - Maherali2009 ER - TY - JOUR AU - Lim, K. T. PY - 2016 DA - 2016// TI - Small molecules facilitate single factor-mediated hepatic reprogramming JO - Cell Rep VL - 15 UR - https://doi.org/10.1016/j.celrep.2016.03.071 DO - 10.1016/j.celrep.2016.03.071 ID - Lim2016 ER - TY - JOUR AU - Gascon, S. AU - Ortega, F. AU - Gotz, M. PY - 2017 DA - 2017// TI - Transient CREB-mediated transcription is key in direct neuronal reprogramming JO - Neurogenesis (Austin) VL - 4 UR - https://doi.org/10.1080/23262133.2017.1285383 DO - 10.1080/23262133.2017.1285383 ID - Gascon2017 ER - TY - JOUR AU - Beyret, E. AU - Belmonte, J. C. I. PY - 2016 DA - 2016// TI - The XEN of reprogramming JO - Cell Res VL - 26 UR - https://doi.org/10.1038/cr.2016.9 DO - 10.1038/cr.2016.9 ID - Beyret2016 ER - TY - JOUR AU - Onder, T. T. PY - 2012 DA - 2012// TI - Chromatin-modifying enzymes as modulators of reprogramming JO - Nature. VL - 483 UR - https://doi.org/10.1038/nature10953 DO - 10.1038/nature10953 ID - Onder2012 ER - TY - JOUR AU - Wang, W. PY - 2011 DA - 2011// TI - Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1 JO - Proc Natl Acad Sci U S A VL - 108 UR - https://doi.org/10.1073/pnas.1100893108 DO - 10.1073/pnas.1100893108 ID - Wang2011 ER - TY - JOUR AU - Chazaud, C. AU - Yamanaka, Y. PY - 2016 DA - 2016// TI - Lineage specification in the mouse preimplantation embryo JO - Development. VL - 143 UR - https://doi.org/10.1242/dev.128314 DO - 10.1242/dev.128314 ID - Chazaud2016 ER - TY - JOUR AU - Wang, Y. PY - 2016 DA - 2016// TI - Conversion of human gastric epithelial cells to multipotent endodermal progenitors using defined small molecules JO - Cell Stem Cell VL - 19 UR - https://doi.org/10.1016/j.stem.2016.06.006 DO - 10.1016/j.stem.2016.06.006 ID - Wang2016 ER - TY - JOUR AU - Yin, Y. AU - Wang, F. AU - Ornitz, D. M. PY - 2011 DA - 2011// TI - Mesothelial- and epithelial-derived FGF9 have distinct functions in the regulation of lung development JO - Development. VL - 138 UR - https://doi.org/10.1242/dev.065110 DO - 10.1242/dev.065110 ID - Yin2011 ER - TY - JOUR AU - Wang, W. M. PY - 2017 DA - 2017// TI - HOXB7 promotes tumor progression via bFGF-induced activation of MAPK/ERK pathway and indicated poor prognosis in hepatocellular carcinoma JO - Oncotarget. VL - 8 ID - Wang2017 ER - TY - JOUR AU - Guo, S. PY - 2014 DA - 2014// TI - Nonstochastic reprogramming from a privileged somatic cell state JO - Cell. VL - 156 UR - https://doi.org/10.1016/j.cell.2014.01.020 DO - 10.1016/j.cell.2014.01.020 ID - Guo2014 ER - TY - JOUR AU - Cho, L. T. PY - 2012 DA - 2012// TI - Conversion from mouse embryonic to extra-embryonic endoderm stem cells reveals distinct differentiation capacities of pluripotent stem cell states JO - Development. VL - 139 UR - https://doi.org/10.1242/dev.078519 DO - 10.1242/dev.078519 ID - Cho2012 ER - TY - JOUR AU - Qian, X. PY - 2016 DA - 2016// TI - DPPA5 supports pluripotency and reprogramming by regulating NANOG turnover JO - Stem Cells VL - 34 UR - https://doi.org/10.1002/stem.2252 DO - 10.1002/stem.2252 ID - Qian2016 ER - TY - JOUR AU - Paca, A. PY - 2012 DA - 2012// TI - BMP signaling induces visceral endoderm differentiation of XEN cells and parietal endoderm JO - Dev Biol VL - 361 UR - https://doi.org/10.1016/j.ydbio.2011.10.013 DO - 10.1016/j.ydbio.2011.10.013 ID - Paca2012 ER - TY - JOUR AU - Artus, J. AU - Panthier, J. J. AU - Hadjantonakis, A. K. PY - 2010 DA - 2010// TI - A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst JO - Development. VL - 137 UR - https://doi.org/10.1242/dev.050864 DO - 10.1242/dev.050864 ID - Artus2010 ER - TY - JOUR AU - Galat, V. PY - 2009 DA - 2009// TI - Developmental potential of rat extraembryonic stem cells JO - Stem Cells Dev VL - 18 UR - https://doi.org/10.1089/scd.2009.0115 DO - 10.1089/scd.2009.0115 ID - Galat2009 ER - TY - JOUR AU - Igarashi, H. PY - 2018 DA - 2018// TI - Sox17 is essential for proper formation of the marginal zone of extraembryonic endoderm adjacent to a developing mouse placental disk JO - Biol Reprod VL - 99 UR - https://doi.org/10.1093/biolre/ioy079 DO - 10.1093/biolre/ioy079 ID - Igarashi2018 ER - TY - JOUR AU - McDonald, A. C. PY - 2014 DA - 2014// TI - Sox17-mediated XEN cell conversion identifies dynamic networks controlling cell-fate decisions in embryo-derived stem cells JO - Cell Rep VL - 9 UR - https://doi.org/10.1016/j.celrep.2014.09.026 DO - 10.1016/j.celrep.2014.09.026 ID - McDonald2014 ER - TY - JOUR AU - Qu, X. B. PY - 2008 DA - 2008// TI - Sox17 facilitates the differentiation of mouse embryonic stem cells into primitive and definitive endoderm in vitro JO - Develop Growth Differ VL - 50 UR - https://doi.org/10.1111/j.1440-169X.2008.01056.x DO - 10.1111/j.1440-169X.2008.01056.x ID - Qu2008 ER - TY - JOUR AU - Hagey, D. W. PY - 2018 DA - 2018// TI - SOX2 regulates common and specific stem cell features in the CNS and endoderm derived organs JO - PLoS Genet VL - 14 UR - https://doi.org/10.1371/journal.pgen.1007224 DO - 10.1371/journal.pgen.1007224 ID - Hagey2018 ER - TY - JOUR AU - Hoffding, M. K. AU - Hyttel, P. PY - 2015 DA - 2015// TI - Ultrastructural visualization of the mesenchymal-to-epithelial transition during reprogramming of human fibroblasts to induced pluripotent stem cells JO - Stem Cell Res VL - 14 UR - https://doi.org/10.1016/j.scr.2014.11.003 DO - 10.1016/j.scr.2014.11.003 ID - Hoffding2015 ER - TY - JOUR AU - Lu, X. PY - 2016 DA - 2016// TI - Variations in mesenchymal-epithelial transition-related transcription factors during reprogramming of somatic cells from different germ layers into iPSCs JO - J Genet Genomics VL - 43 UR - https://doi.org/10.1016/j.jgg.2016.04.001 DO - 10.1016/j.jgg.2016.04.001 ID - Lu2016 ER - TY - JOUR AU - Samavarchi-Tehrani, P. PY - 2010 DA - 2010// TI - Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming JO - Cell Stem Cell VL - 7 UR - https://doi.org/10.1016/j.stem.2010.04.015 DO - 10.1016/j.stem.2010.04.015 ID - Samavarchi-Tehrani2010 ER - TY - JOUR AU - Li, R. PY - 2010 DA - 2010// TI - A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts JO - Cell Stem Cell VL - 7 UR - https://doi.org/10.1016/j.stem.2010.04.014 DO - 10.1016/j.stem.2010.04.014 ID - Li2010 ER - TY - JOUR AU - Martin-Lopez, M. PY - 2017 DA - 2017// TI - p73 is required for appropriate BMP-induced mesenchymal-to-epithelial transition during somatic cell reprogramming JO - Cell Death Dis VL - 8 UR - https://doi.org/10.1038/cddis.2017.432 DO - 10.1038/cddis.2017.432 ID - Martin-Lopez2017 ER - TY - JOUR AU - Zhang, J. PY - 2018 DA - 2018// TI - The oncogene Etv5 promotes MET in somatic reprogramming and orchestrates epiblast/primitive endoderm specification during mESCs differentiation JO - Cell Death Dis VL - 9 UR - https://doi.org/10.1038/s41419-018-0335-1 DO - 10.1038/s41419-018-0335-1 ID - Zhang2018 ER - TY - JOUR AU - Brix, J. AU - Zhou, Y. AU - Luo, Y. PY - 2015 DA - 2015// TI - The epigenetic reprogramming roadmap in generation of iPSCs from somatic cells JO - J Genet Genomics. VL - 42 UR - https://doi.org/10.1016/j.jgg.2015.10.001 DO - 10.1016/j.jgg.2015.10.001 ID - Brix2015 ER - TY - JOUR AU - Luu, P. L. PY - 2018 DA - 2018// TI - Rules governing the mechanism of epigenetic reprogramming memory JO - Epigenomics. VL - 10 UR - https://doi.org/10.2217/epi-2017-0098 DO - 10.2217/epi-2017-0098 ID - Luu2018 ER - TY - JOUR AU - Nashun, B. AU - Hill, P. W. AU - Hajkova, P. PY - 2015 DA - 2015// TI - Reprogramming of cell fate: epigenetic memory and the erasure of memories past JO - EMBO J VL - 34 UR - https://doi.org/10.15252/embj.201490649 DO - 10.15252/embj.201490649 ID - Nashun2015 ER - TY - JOUR AU - Nefzger, C. M. PY - 2017 DA - 2017// TI - Cell type of origin dictates the route to pluripotency JO - Cell Rep VL - 21 UR - https://doi.org/10.1016/j.celrep.2017.11.029 DO - 10.1016/j.celrep.2017.11.029 ID - Nefzger2017 ER - TY - JOUR AU - Mulvey, C. M. PY - 2015 DA - 2015// TI - Dynamic proteomic profiling of extra-embryonic endoderm differentiation in mouse embryonic stem cells JO - Stem Cells VL - 33 UR - https://doi.org/10.1002/stem.2067 DO - 10.1002/stem.2067 ID - Mulvey2015 ER - TY - JOUR AU - Spyrou, J. AU - Gardner, D. K. AU - Harvey, A. J. PY - 2019 DA - 2019// TI - Metabolism is a key regulator of induced pluripotent stem cell reprogramming JO - Stem Cells Int VL - 2019 UR - https://doi.org/10.1155/2019/7360121 DO - 10.1155/2019/7360121 ID - Spyrou2019 ER -