Skip to main content
Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Phenotype instability of hepatocyte-like cells produced by direct reprogramming of mesenchymal stromal cells

Fig. 7

Experimental schematic for iHEP transplantation into the AhCreMdm2fl/fl mouse model (a). Kaplan-Meier survival plot (b). Gross morphology and comparative H&E staining of the liver and spleen of iHEP vs PBS transplanted mice (c). Confirmation of iHEP engraftment showing expression of GFP (small boxes represent magnified regions), Foxa2, and HNF4ɑ (d). Characterization of engrafted iHEPs utilizing dual immunofluorescent staining for GFP and ɑSMA, EpCAM, or albumin (e). *p < 0.05. Scale bars 200 μm

Back to article page