Fig. 3
From: Runx1t1 promotes the neuronal differentiation in rat hippocampus
Knockdown of Runx1t1 decreased neuronal differentiation of hippocampal NSCs. The gene and protein expression of Runx1t1 in the RNAi group was significantly lower than the mock-infected and NC groups (a, b). Compared to the mock and NC groups, less Tuj1-positive cells were detected after treatment with LV3-Runx1t1-RNAi, and the length of processes of Tuj1-positive cells became shorter, lesser, and even less evident (c–k). Scale bar = 50 μm. The numbers of Tuj1-positive cells showed a significant difference between the mock-infected and LV3-NC groups with an LV3-Runx1t1-RNAi group (l). P < 0.05. NC, negative control; RNAi, RNA interference