Fig. 4

In vivo repopulating potential of cord blood CD34⁺ cells expressing different levels of CD18. a hCD45⁺ levels at different months post-transplant in the BM of recipient mice transplanted with purified CD34⁺CD18^high (n = 6; black circles) or CD34⁺CD18^low/neg (n = 4; open squares) populations. Graphic represents the percentage of positive cells in total BM. b Lineage distribution represented as the percentage of human CD34⁺, CD19⁺, and CD33⁺ and c the percentage of CD18⁺ cells in these populations determined in mouse BM at 3 mpt. d hCD45⁺ levels at 3 mpt in the BM of secondary recipients that were transplanted with 3–5 × 10⁶ purified hCD45⁺ cells obtained from primary recipients at 3 mpt (CD34⁺CD18^high, n = 5; CD34⁺CD18^low/neg, n = 3). Graphic represents the percentage of positive cells in total BM. The significance of differences between groups is expressed as P < 0.05 (*)