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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Exosomes derived from mesenchymal stem cells inhibit neointimal hyperplasia by activating the Erk1/2 signalling pathway in rats

Fig. 4

MSC-Exo activated the Erk1/2 signalling pathway. a Western blot analysis of the expression of Erk1/2 and phosphorylated Erk1/2. b Cell viability analysis of the growth of EC that were given combined treatment with MSC-Exo and SCH772984. c Cell scratch experiment analysis of the migration of EC that were given combined treatment of MSC-Exo and SCH772984. d Quantitative analysis of the migration ratio of the indicated EC. e Immunofluorescence analysis of the number of Ki67-positive EC (green) after treatment with MSC-Exo and SCH772984 (magnifications, × 400; scale, 200 μm). f Quantitative analysis of the proportion of Ki67-positive EC. g Western blot analysis of the expression of the indicated proteins. *P < 0.05, **P < 0.01 and ***P < 0.001. All figures represent the average of three sets of independent experiments

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Stem Cell Research & Therapy

ISSN: 1757-6512