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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: MiR-153 reduces stem cell-like phenotype and tumor growth of lung adenocarcinoma by targeting Jagged1

Fig. 1

Enhanced miR-153 expression attenuates the stemness properties of lung cancer cells. a miR-153 expression in SPC-A-1 cells after miR-153 overexpression was determined by qPCR. b Tumor sphere formation capacity of SPC-A-1 cells was analyzed after miR-153 overexpression. Scale bar, 100 μm. c Stem cell markers (MSI-1 and Snail) expression in control and miR-153-overexpressing cells was analyzed by quantitative PCR. d The MSI-1 and snail protein levels in indicated cells were determined by western blot. e Stem cell marker CD133 expression was determined by immunofluorescence. Scale bar, 50 μm. Data shown are mean ± s.d. of three independent experiments. *P < 0.05, ***P < 0.001 by two tailed Student’s t test

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Stem Cell Research & Therapy

ISSN: 1757-6512