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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Regenerative and protective effects of dMSC-sEVs on high-glucose-induced senescent fibroblasts by suppressing RAGE pathway and activating Smad pathway

Fig. 6

dMSC-sEVs improved the proliferation, migration, and differentiation abilities of fibroblasts. a CCK-8 analysis was applied to measure the effect of dMSC-sEVs on the proliferation of HG aged HDFs (n = 5). b, c Effects of the dMSC-sEVs on the cell cycle progression of HG aged HDFs (n = 5). d, e The migration ability has been determined by migration assay (n = 5). Scale bar = 200 μm. f The expression level of α-SMA and collagen I and the quantification results. The results were normalized to GAPDH expression (n = 5). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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Stem Cell Research & Therapy

ISSN: 1757-6512