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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Bone marrow mesenchymal stem cells improve bone erosion in collagen-induced arthritis by inhibiting osteoclasia-related factors and differentiating into chondrocytes

Fig. 4

The distribution of GFP-labeled bone marrow mesenchymal stem cells (BMSCs) in the synovial cartilage and bone marrow 3 days after transplantation. a BMSCs were distributed in the bone marrow and synovial membrane but not in the cartilage and bone tissue. The yellow arrow denotes bone tissue; orange, synovial tissue; red, cartilage tissue; and green, bone marrow cavity (× 40). b GFP+ cells in the bone marrow (× 600). c GFP+ cells in the synovium (× 600). d No GFP+ cells were observed at 3 days in the cartilage and bone tissue (× 600). e After 11 days of transplantation, GFP-positive cells were observed in the articular cartilage, primarily spindle cells (× 600). f After 42 days of transplantation, GFP-positive cells were observed in the articular cartilage and bone tissues, primarily comprising oval and spherical cells (× 600). The red arrows denote cartilage tissue; yellow, bone tissues; and green, bone marrow cavities

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