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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Cord blood-endothelial colony forming cells are immunotolerated and participate at post-ischemic angiogenesis in an original dorsal chamber immunocompetent mouse model

Fig. 1

CB-ECFCs are hypoimmunogenic and exert immunosuppressive properties. a 105 PBMCs were used as HLA-mismatched responder cells and stimulated by either various ratios of CB-ECFCs or by 0.5 × 105 irradiated LCL cells as positive control. Data are given as histograms representing mean ± SEM of alloproliferation percentage obtained with 4 distinct PBMCs and 4 distinct CB-ECFCs (#1, #2, #3, #4); *p < 0.05. b 105 PBMCs were used as HLA-mismatched responder cells, stimulated by 0.5 × 105 irradiated LCL, and concomitantly inhibited by various ratios of CB-ECFCs as third-party cells. Data are represented as a linear dose effect of CB-ECFC number on alloproliferation percentage, obtained with 6 distinct PBMCs and 3 distinct CB-ECFCs (#5, #6, #7); the alpha angle represents the difference between the slope and 0

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